All protein sources of consumption appear to enhance feelings of fullness.
Although metabolism is important, any mechanism by which we reduce the intake of food and calories can assist with weight loss. Dietary protein has long been suggested as a means of enhancing satiety. Dietary protein has long been considered the most satiating macronutrient, yet there is little evidence on whether the effects observed are attributable to the protein or the concomitant manipulation of carbohydrates and fat. If protein could promote satiety or fullness, it would enhance weight loss. If it could reduce hunger and overeating, it could be a key part of many meals to include breakfast.
I wrote a prior article on plant protein and satiety. The question is if the mechanism and effect were translatable to the other sources of protein. It has been suggested that protein increases Leptin(), Protein YY(,) and Ghrelin(,,). No matter the mechanism, all of these studies that have shown an increase in satiety with proteins of multiple types and there is no reason to believe that this effect is not a macronutrient effect caused by all sources of proteins(,). The findings the studies suggest that modulating the release of endogenous satiety factors, such as Protein YY, leptin, and ghrelin, through alteration of protein consumption could provide a rational therapy for obesity. Studies are clear that an increase in dietary protein from 15% to 30% of total calories produces a sustained decrease in caloric intake that may be mediated by increased central nervous system leptin sensitivity and results in significant weight loss and this anorexic effect of protein may contribute to the weight loss produced by low-carbohydrate diets.
The bottom line: Eating protein has also been shown to help you feel more full and prevent you from overeating. The most satiating macronutrient appears to be dietary protein. Alteration of specific diet constituents to increase protein consumption to 30% could provide a rational therapy for obesity. No matter whether the mechanism is ghrelin, leptin, or Protein YY, the effect is the same. Increased protein consumption and a lower carbohydrate appear to lower resistance and increase satiety.